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Welsh broadcaster Nicola Heywood Thomas has died after an illness.
The host of the Radio Wales Arts Show, 67, who lived in Cardiff, began her career at BBC Wales straight from university as a news researcher.
She worked for Wales Today as a sub-editor, reporter and presenter but was perhaps best known for her 18 years as HTV's main news presenter.
The mother-of-three had continued to broadcast as recently as February.
BBC Radio Wales editor Carolyn Hitt said said Ms Heywood Thomas had been undergoing "very gruelling chemotherapy".
Ms Heywood Thomas' on-screen work at HTV - the precursor to ITV Wales - also included reporting and fronting current affairs programmes and documentaries.
She was a BAFTA Cymru award winner.
After leaving HTV, she became closely associated with arts coverage at BBC Wales, as well as working with BBC Radio 3.
ITV Wales said in a tribute she was one of its "most iconic faces".
"She anchored Wales at Six for more than 15 years. Thoughts are with all her friends and colleagues tonight".
Ms Hitt said Radio Wales was "deeply saddened" by the news of her death.
She said Ms Heywood Thomas had been the voice of arts coverage in Wales for more than 25 years and was "hugely respected and admired".
The broadcaster brought to her work a journalist's insight and an arts fan's passion, she said.
"She was fascinated by performers and artists and the stories behind the work they created, and always looked for imaginative ways to communicate these stories," Ms Hitt said.
"Nicola championed Welsh culture and hated the idea that the arts were some kind of posh pursuit for the elite."
Ms Hitt praised her colleague for being hard working and "fantastic company".
"We have been astounded and deeply touched in recent months to witness her dedication to her Radio Wales programmes, even though she was facing such challenging health issues," she said.
"We will miss her creativity, her commitment and the warmth of her friendship.
"Wales has lost one of its greatest broadcasters."
Friend Hugh Canning posted on Twitter that the "broadcaster extraordinaire" had died.
Mr Canning said Ms Heywood Thomas was his oldest friend, adding: "We met in my first year at Oxford - 1972 - when she was 16 and I was 18 and we have been friends ever since.
"I owe her so much. RIP Nicola."