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Super Bowl champions the Kansas City Chiefs will begin the defence of their title against the Baltimore Ravens at Arrowhead Stadium on Thursday, 5 September.
The NFL announced the 2024-25 season will start with a rematch of January's AFC championship game, which the Chiefs won 17-10.
Kansas beat the San Francisco 49ers 25-22 in overtime to win their third Super Bowl in five years in February.
The Chiefs are chasing a third consecutive Super Bowl title and boast a threatening attack, including last season's Most Valuable Player (MVP) Patrick Mahomes.
The NFL will unveil the entire 2024-25 schedule on Wednesday.