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More than 130,000 civil servants voted to go on strike next month in a dispute over pay, pensions and job security.
The PCS union said its members voted to take action on 28 April to increase the pressure on the government and were "not backing down".
PCS general secretary Mark Serwotka said: "Ministers need to resolve the dispute by putting money on the table."
Members of the union last walked out on Budget day.