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By Thomas Mackintosh
BBC News
Thousands of passengers face flight cancellations as major airlines saw dozens of Boeing jets grounded after a mid-flight blowout over Oregon.
The US aviation regulator said 171 Boeing 737 Max 9s must be grounded for checks after part of an Alaska Airlines plane's fuselage fell off on Friday.
Alaska said about 23,000 passengers had flights cancelled on Saturday, with further disruption expected.
United Airlines and Turkish Airlines have also grounded planes.
It follows regulator Federal Aviation Administration (FAA) ordering "immediate inspections" of 737 Max 9s worldwide.
Required inspections would take around four to eight hours per aircraft, it said.
Boeing said it welcomed the FAA's decision, adding its teams were in close contact with the regulator.
During Friday's incident, Alaska Airlines flight 1282 from Portland, Oregon to Ontario, California, reached 16,000ft (4,876m) when it began an emergency descent, according to flight tracking data.
Passengers on board said a large section of the plane's outer shell fell to the ground shortly after take-off.
Images sent to news outlets show the night sky and lights of Portland visible through the gap in the fuselage, with insulation material and other debris also seen.
One passenger said the gap was "as wide as a refrigerator" while another said a child's shirt was ripped off in the wind as the plane made its emergency landing.
The plane, carrying 177 passengers and crew, landed safely back in Portland. Alaska said several passengers were injured, but not seriously.
"My heart goes out to those who were on this flight - I am so sorry for what you experienced," Alaska's CEO Ben Minicucci said after the firm volunteered to ground 65 of its 737 Max 9 planes.
"I am so grateful for the response of our pilots and flight attendants," he added.
Alaska later said that, as of Saturday afternoon, it had cancelled 160 flights.
The airline said on Saturday 18 of its 737 Max 9 planes had received "in-depth inspections as part of heavy maintenance checks" and were returned to service - but following the FAA's orders these have since been "pulled from service".
"We are in touch with the FAA to determine what, if any, further work is required before these aircraft are returned to service," Alaska said in a statement.
It added: "The aircraft involved in flight 1282 was delivered to us on 31 October. The part of the aircraft involved in this event is called a plug door - a specific panel of the fuselage near the rear of the aircraft."
United Airlines says it has carried out the inspections required by the FAA on some of its 79 737 Max 9 planes.
Removing some of the aircraft from service was expected to cause about 60 cancellations on Saturday, the airline said in a statement.
Turkish Airlines has grounded five of its 737 Max 9s.
Flydubai told said its three 737 Max 9s had a "different configuration with mid-aft cabin exits" compared to the Alaska Airline planes and have completed recent safety checks.
British regulator Civil Aviation Authority (CAA) said there are no registered Boeing 737 Max 9 planes in the UK and therefore the impact would be "minimal".
"We have written to all non-UK and foreign permit carriers to ask for confirmation that inspections have been undertaken prior to any operation into UK airspace," a CAA spokesman said.
In the US, the National Transportation Safety Board (NTSB) has taken charge of the Alaska investigation and its chair confirmed no passenger had been sat next to the affected section.
"We are very, very fortunate here that this didn't end up in something more tragic," Jennifer Homendy said.
Meanwhile, authorities are still searching for the plug door, which they believe fell to the ground in the community of Cedar Hills, about 11 km (seven miles) west of central Portland.
Boeing's 737 Max has been described as "the most scrutinised transport aircraft in history" after a series of safety issues.
The Max was grounded in March 2019 for a year-and-a-half after two of the type crashed in similar circumstances to each other killing those on board.
Aviation expert John Strickland said the Alaska Airlines incident was very different to those crashes, adding that since the 737 Max came back into service it had "an enormous safety record".
"While we know little evidence of why this section of the fuselage has come out - this has nothing to do with the aircraft being grounded for 18 months," he told BBC News.
"But, it is natural Alaska Airlines is taking a cautious approach grounding its fleet"
More recently, Boeing said it would increase the pace of 737 Max deliveries after resolving a supply error that required it to conduct lengthy inspections of new planes and its inventory.
About 1,300 737 Max aircraft have been delivered to customers, Boeing data shows.
Last month, the FAA urged airlines to inspect Max models for a possible loose bolt in rudder control systems.