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Ethel Kennedy, a human rights advocate and the widow of Robert F Kennedy, has died aged 96, her family says.
A matriarch of one of America's most famous political dynasties, she died on Wednesday after suffering a stroke a week ago, the family member said.
Her grandson, Joe Kennedy, posted a statement online to announce the passing of "our amazing grandmother".
She was by her husband Robert F Kennedy’s side when the Democratic presidential candidate was fatally shot in a Los Angeles hotel kitchen in 1968. Five years earlier, her brother-in-law, President John F Kennedy, was assassinated in Dallas, Texas.
She founded the Robert F Kennedy Human Rights foundation months later, while still pregnant with their 11th child.
Joe Kennedy posted on X, formerly Twitter, of his grandmother: "It is with our hearts full of love that we announce the passing of our amazing grandmother, Ethel Kennedy.
"Along with a lifetime's work in social justice and human rights, our mother leaves behind nine children, 34 grandchildren, and 24 great-grandchildren, along with numerous nieces and nephews, all of whom love her dearly."
He described her as a "devout Catholic", adding: "We are comforted in knowing she is reunited with the love of her life, our father, Robert F Kennedy; her children David and Michael; her daughter-in-law Mary; her grandchildren Maeve and Saoirse; and her great-grandchildren Gideon and Josie.
"Please keep her in your hearts and prayers."