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The former Tory deputy chairman has been suspended from the party after "refusing to apologise" for comments aimed at Sadiq Khan.
Lee Anderson told GB News on Friday "Islamists" had "got control" of the mayor of London.
Mr Khan described the remarks as "pouring fuel on the fire of anti-Muslim hatred".
Losing the Tory whip essentially expels Mr Anderson from his party in Parliament.
Pressure had been mounting on Rishi Sunak to take action over the comments from the Ashfield MP after Mr Khan criticised a "deafening silence" from the prime minister and his Cabinet.
Just over an hour after Mr Khan's criticism, a spokesperson for the Tory party's chief whip Simon Hart said: "Following his refusal to apologise for comments made yesterday, the chief whip has suspended the Conservative whip from Lee Anderson MP."
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