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Dave leads this year's MOBOs nominations with five, as the awards show returns with its first live show since 2017.
Newcomer Central Cee comes in close behind with four nominations.
Little Simz, Arlo Parks, Ghetts and Cleo Sol have three each, including Best Female Act and Album of the Year.
The awards, which have celebrated music of black origin since 1996, will take place in Coventry on 5 December.
Mahalia and Nines won two awards each at last year's remote event, which was only streamed online.
It's not a bad MOBOs debut for London rapper Central Cee with four nominations.
They include Best Male Act and Song of the Year for Commitment Issues.
Previous winners also include Stormzy - who won three awards in 2017, and Kano, who won best album in 2016.
Other names honoured in recent events include Krept & Konan, Nicola Adams, Skepta, Lenny Henry, Ms Dynamite and Sam Smith.
People can now vote for who they want to win on the MOBOs website.
Soul singer Cleo Sol is recognised for her latest album Mother, by being in the running this year for Best R&B/Soul Act, Best Female Act, and Album of The Year.
This year's ceremony will also see the MOBOs first award for Best Drill Act.
Organisers say they want to "recognise the cultural and urgent force that the genre has become over last few years".
The MCs nominated include Headie One, Tion Wayne, Unknown T, Digga D and M1llionz.
"The past 20 months have been extremely challenging for artists everywhere," explains Kanya King CBE, the founder and boss of MOBO Group.
"As always we are seeing creatives rise up and adapt, even in a global pandemic."
When will it be on?
The ceremony will take place on Sunday 5 December at Coventry Building Society Arena.
It will be live-streamed on YouTube, with BBC One broadcasting a behind-the-scenes show with interviews and performances.
BBC Radio 1Xtra will also be covering the awards, with DJ Target's weekday shows bringing performances and interviews with this year's nominees and winners.
The nominees in full
Best Male Act
Best Female Act
Album of the year
Arlo Parks - Collapsed in Sunbeams
Dave - We're All Alone in this Together
Ghetts - Conflict of Interest
Song of the year
Central Cee - Commitment Issues
Dave featuring Stormzy - Clash
Enny featuring Amia Brave - Peng Black Girls
Pa Salieu featuring Backroad Gee - My Family
Tion Wayne and Russ Millions, Arrdee, Bugzy Malone, Buni, Darkoo, E1 (3x3), Fivio Forei & ZT (3X3) - Body (remix)
Best newcomer
Video of the year
Bree Runway - Hot Hot (Directed by Jocelyn Anquetil)
Fredo featuring Dave - Money Talks (Directed by Edem Wornoo)
Little Simz featuring Cleo Sol - Woman (Directed by Little Simz)
M1llionz - Lagga (Directed by Teeeezy C)
Pa Salieu Featuring Backroad Gee - My Family (Directed by Femi Ladi)
Slowthai featuring A$AP Rocky - Mazza (Directed by The Rest)
Best R&B/soul act
Best grime act
Best hip-hop act
Best drill act
Best international act
Young Stoner Life (Young Thug & Gunna)
Best performance in a TV show/film
Ashley Thomas as Henry in Them
Damson Idris as Franklin Saint in Snowfall
Daniel Kaluuya as Fred Hampton in Judas & the Black Messiah
Letitia Wright as Altheia Jones-LeCointe in Small Axe
Micheal Ward as Franklyn in Small Axe