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Nadhim Zahawi told BBC Breakfast that there was no place for Islamophobia in the Conservative party, following claims by a Muslim MP that her faith had been an issue when she was sacked as a minister.
No 10 said the Prime Minister took the claims very seriously.
Nusrat Ghani said she was told her status as a Muslim woman had made colleagues "feel uncomfortable". She lost her job as transport minister in a reshuffle in 2020.