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Liverpool were thrashed by Napoli in their first Champions League Group A game on a night to forget in Italy.
Jurgen Klopp's side were 3-0 down at half time but it could easily have been more as Alisson saved a penalty and Virgil van Dijk made a goalline block.
Piotr Zielinski put Napoli ahead from the spot in the fifth minute after Victor Osimhen had hit the post.
Andre-Frank Anguissa and Giovanni Simeone extended Napoli's lead, before Zielinski scored again after the break.
It was a terrible opening half from Liverpool as Joe Gomez struggled to deal with Osimhen and was relieved when the Napoli forward trudged off with an injury before half-time.
His replacement, Simeone, needed just three minutes to score on his Champions League debut as Liverpool looked shell-shocked by the home side's relentless forward approach.
There were chances for the visitors - Van Dijk had a header well saved, Mohamed Salah struck an effort at the goalkeeper and a teasing cross bounced dangerously off Harvey Elliott's knee at the back post.
But Liverpool were sloppy in possession - even Salah mis-controlled a good pass from Trent Alexander-Arnold when well-placed in the box - and their defensive mistakes were punished by an expressive Napoli side.
Any hope of a second-half comeback were over when Zielinski chipped a finish over Alisson from close range to make it 4-0 and though Luis Diaz curled in for an immediate response and came close with a diving header, Liverpool were deservedly beaten.
Deadline-day signing Arthur Melo came on for his debut late in the second half and fellow midfielder Thiago returned from injury to make a brief cameo, but Liverpool will head home having now won just two of their last seven matches in all competitions.
'That's an embarrassing 45 minutes'
From the very first minute, Liverpool were on the back foot in Naples.
Osimhen gave them an early warning when he rounded Alisson and fired against the post from a tight angle.
Napoli, though, needed only five minutes to take the lead when Zielinski coolly slotted in his penalty after handball against James Milner.
A typical Klopp side would have been expected to bounce back immediately, but this season Liverpool have looked tired, demotivated and seriously out of form.
What followed instead was only humiliation as the hosts were ruthless, while Liverpool made numerous mistakes and struggled to get a stronghold of the game with talisman Salah having several poor touches.
Osimhen ran the struggling Gomez ragged and Napoli could have scored at least another two goals, were it not for a goalline clearance from Van Dijk to deny Khvicha Kvaratskhelia and a penalty save from Allison to thwart Osimhen after the lively frontman had been caught by Van Dijk.
Former Fulham midfielder Anguissa doubled Napoli's lead in style as a quick one-two ripped apart Liverpool's defence, before Kvaratskhelia set up Simeone's third.
When the whistle finally blew for the break, Klopp sprinted straight down the tunnel.
The last time Liverpool conceded three goals in the first half of a Champions League game was in October 2014 when they lost 3-0 to Real Madrid.
"That's an embarrassing 45 minutes," former Manchester United defender Rio Ferdinand said on BT Sport,
Liverpool at least improved in the second half but Napoli remained in complete control.
The impressive Zielinski added the fourth two minutes after the restart and Diaz's goal in the 49th minute was no consolation for the disappointing six-time European champions.
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Napoli
Squad number1Player nameMeret
Squad number22Player nameDi Lorenzo
Squad number13Player nameRrahmani
Squad number3Player nameKim Min-Jae
Squad number17Player nameOlivera
Squad number99Player nameZambo Anguissa
Squad number68Player nameLobotka
Squad number21Player namePolitano
Squad number20Player nameZielinski
Squad number77Player nameKvaratskhelia
Squad number9Player nameOsimhen
Squad number6Player nameMário Rui
Squad number7Player nameElmas
Squad number11Player nameLozano
Squad number18Player nameSimeone
Squad number23Player nameZerbin
Liverpool
Squad number1Player nameAlisson
Squad number66Player nameAlexander-Arnold
Squad number2Player nameGomez
Squad number4Player namevan Dijk
Squad number26Player nameRobertson
Squad number19Player nameElliott
Squad number3Player nameFabinho
Squad number7Player nameMilner
Squad number11Player nameMohamed Salah
Squad number9Player nameRoberto Firmino
Squad number23Player nameDíaz
Squad number6Player nameThiago Alcántara
Squad number20Player nameDiogo Jota
Squad number27Player nameNúñez
Squad number29Player nameArthur
Squad number32Player nameMatip
Line-ups
Napoli
Formation 4-2-3-1
- 1Meret
- 22Di Lorenzo
- 13RrahmaniBooked at 66mins
- 3Kim
- 17OliveraSubstituted forMário Ruiat 74'minutes
- 99Zambo Anguissa
- 68Lobotka
- 21PolitanoSubstituted forLozanoat 58'minutes
- 20ZielinskiSubstituted forElmasat 74'minutes
- 77KvaratskheliaSubstituted forZerbinat 57'minutes
- 9OsimhenSubstituted forSimeoneat 41'minutes
Substitutes
- 5Nunes Jesus
- 6Mário Rui
- 7Elmas
- 11Lozano
- 18Simeone
- 23Zerbin
- 30Sirigu
- 55Östigard
- 59Zanoli
- 70Gaetano
- 81Raspadori
- 91Ndombélé
Liverpool
Formation 4-3-3
- 1Alisson
- 66Alexander-Arnold
- 2GomezSubstituted forMatipat 45'minutes
- 4van DijkBooked at 18mins
- 26Robertson
- 19ElliottSubstituted forArthurat 77'minutes
- 3Fabinho
- 7MilnerBooked at 10minsSubstituted forThiago Alcántaraat 63'minutes
- 11SalahSubstituted forJotaat 63'minutes
- 9FirminoSubstituted forNúñezat 62'minutes
- 23Díaz
Substitutes
- 6Thiago Alcántara
- 13Adrián
- 20Jota
- 21Tsimikas
- 27Núñez
- 29Arthur
- 32Matip
- 43Bajcetic
- 47Phillips
- 95Davies
Referee:Carlos del Cerro Grande
Live Text
Match ends, Napoli 4, Liverpool 1.
Second Half ends, Napoli 4, Liverpool 1.
Corner, Napoli. Conceded by Andrew Robertson.
Corner, Napoli. Conceded by Andrew Robertson.
Foul by Thiago (Liverpool).
Giovanni Simeone (Napoli) wins a free kick in the defensive half.
Attempt blocked. Diogo Jota (Liverpool) left footed shot from the right side of the box is blocked.
Corner, Liverpool. Conceded by Giovanni Di Lorenzo.
Attempt blocked. Arthur (Liverpool) right footed shot from outside the box is blocked. Assisted by Diogo Jota.
Attempt saved. Alessio Zerbin (Napoli) right footed shot from outside the box is saved in the bottom right corner. Assisted by André-Frank Zambo Anguissa.
Corner, Liverpool. Conceded by Mário Rui.
Offside, Napoli. André-Frank Zambo Anguissa tries a through ball, but Giovanni Simeone is caught offside.
Arthur (Liverpool) wins a free kick in the defensive half.
Foul by Mário Rui (Napoli).
Attempt blocked. Giovanni Simeone (Napoli) left footed shot from the centre of the box is blocked. Assisted by Alessio Zerbin.
Thiago (Liverpool) wins a free kick in the defensive half.
Foul by André-Frank Zambo Anguissa (Napoli).
Substitution, Liverpool. Arthur replaces Harvey Elliott.
Foul by Darwin Núñez (Liverpool).
Alex Meret (Napoli) wins a free kick in the defensive half.
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