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Long-running Australian soap Neighbours will come to an end this summer after 37 years, producers have confirmed.
The announcement follows the news that UK broadcaster Channel 5 was dropping the show from its schedules.
That decision left producers with a funding gap, as the British network was a key broadcast partner in the series.
Writing on the programme's official Twitter account, producers said they were "so sorry" but had "no option but to rest the show".
"We are so sorry to say that after nearly 37 years and almost 9,000 episodes broadcast we have to confirm that Neighbours will cease production in the summer," they said in a statement.
"Following the loss of our key broadcast partner in the UK and despite an extensive search for alternative funding, we simply have no option but to rest the show.
"To our amazing, loyal fans, we know this is a huge disappointment, as it is to all of us on the team. We thank you for all your messages and support and promise to end the show on an incredible high."
Neighbours aired on Channel 5 for more than a decade, and was previously broadcast on the BBC.
When it was announced earlier this year that the show's future was under threat, singer and former Neighbours star Jason Donovan said the soap "changed the Australian television landscape".
Set and filmed in Melbourne, Neighbours was first broadcast in Australia in 1985 and launched on BBC One a year later.
It became a huge hit in the UK and in Australia, and helped launch the career of numerous stars, including Kylie Minogue, Jason Donovan, Guy Pearce and later Margot Robbie.
Channel 5 previously said it knew the decision to axe the show - which attracts more than one million viewers per day in the UK - would disappoint many.
But it added its "current focus is on increasing our investment in original UK drama, which has strong appeal for our UK viewers".
Actor and singer Donovan, who played Scott Robinson from 1986 to 1989, wrote on Twitter: "It launched many careers over decades including mine.
"Engaged and entertained audiences for generations. Hoping that it will find a new home with another UK broadcaster and continue to provide opportunity and entertainment."
Neighbours stars over the years
The soap has featured many notable Australian actors, actresses and performers over the years, many of whom have gone on to have glittering careers.
Perhaps the most high profile of these stars to make her name on Neighbours is singer Kylie Minogue, who acted in the early years of the soap, playing Charlene between 1986 and 1988.
Other people to come off the Ramsay Street set include Oscar winner and Gladiator star Russell Crowe, musician Jason Donovan and actor Guy Pearce.
More recently, the show featured Suicide Squad star Margot Robbie from 2008 to 2011 and Liam Hemsworth between 2007 and 2008.
Other people to have made their names from appearing on the show over the years include the singers Natalie Imbruglia, Holly Vallance and Delta Goodrem.