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At least three people, including the suspect, have died and six others are injured after a shooting at a high school in St Louis, Missouri.
The gunman entered Central Visual & Performing Arts High School shortly after 09:00 local time (13:00 GMT) on Monday.
The doors of the school building were locked and it was not immediately clear how the suspect entered.
St Louis Public Schools have said police "quickly stopped" the gunman.
The suspect, believed to be in his 20s, exchanged gunfire with police and later succumbed to his injuries.
Neither his motive nor his connection to the school of about 400 students has yet been identified.
A teenage girl was pronounced dead inside the school, while one woman died in hospital, police told local media.
Students were running out of the school when officers arrived and said the attacker had a "long gun", according to the city's police commissioner Michael Sack.
He said seven security workers on site had acted quickly to notify other staff and contact police.
"This is a heart-breaking day for all of us," he said.
First-year student Raven Terry told the KMOV local news station the attacker had walked up to a friend and asked her "You ready to die?"
"They said it was a student who was doing the shooting," Terry said of the police response.
"We just ran real, real fast... and we were just crying all shaken up about it."
Taniya Gholston, 16, told the St Louis Post-Dispatch newspaper that the gunman entered a classroom she was in and tried to shoot her.
"I was trying to run and I couldn't run," she claimed. "Me and him made eye contact but I made it out because his gun got jammed."
"But we saw blood on the floor," she added.
Those injured are said to be suffering from gunshot wounds, shrapnel injuries and cardiac arrest.
"Our children shouldn't have to experience this," St Louis Mayor Tishaura Jones said at a news conference after the shooting.
"They shouldn't have to go through active shooter drills in case something happens. And unfortunately, that happened today."
Data from the Education Week outlet show there have been at least 35 school shootings, in which at least one person was killed or injured, so far this year.
Earlier on Friday, a teenager in Michigan pleaded guilty to 24 charges, including terrorism and first-degree murder, after a rampage at his high school last November.