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Wes Streeting has asked the health secretary why he was not negotiating with NHS staff over a strike due later this month, and accused him of using nurses as a scapegoat.
Steve Barclay told the shadow heath secretary said his door was "open" and he was not setting preconditions to talks, adding Labour was not supporting a 19% pay rise.
The three main ambulance unions - Unison, GMB and Unite - are due to strike in England and Wales over pay on 21 and 28 December, affecting non-life threatening calls.
Live: Thousands of ambulance workers to strike before Christmas