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Warrington are to play their home Super League game against Wigan Warriors in Las Vegas in 2025.
England women will also play their Australian counterparts at NFL side the Las Vegas Raiders' Allegiant Stadium home.
There will also be two NRL games, with New Zealand Warriors taking on Canberra Raiders and Cronulla Sharks playing Penrith Panthers.
All four games will be played on Saturday, 1 March.
This will be the second year when Vegas hosts action from the NRL after Brisbane Broncos, Manly Sea Eagles, South Sydney Rabbitohs and Sydney Roosters played there as part of the NRL's opening weekend in 2024.
"I think it's really exciting for the game that two great foundation clubs get to play over there in the States," Warrington head coach Sam Burgess told BBC Sport.
"We saw the NRL get over there and play two games at the beginning of the year, and it was hugely successful.
"A lot of English fans went over there to watch those games, so it will be amazing to see some Super League action.
"We're looking forward to it, it'll be a great week, and the team are certainly excited about that."
England women's captain Jodie Cunningham added: "I think it’s fantastic that the NRL have recognised the importance of the women’s game in this way.
"We all watched the NRL games in Vegas at the start of this season and it was so exciting to see the impact they made."